Promoter Of A Gene

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Promoter (genetics) - Wikipedia

(7 days ago) As promoters are typically immediately adjacent to the gene in question, positions in the promoter are designated relative to the transcriptional start site, where transcription of DNA begins for a particular gene (i.e., positions upstream are negative numbers counting back from -1, for example -100 is a position 100 base pairs upstream).

https://en.wikipedia.org/wiki/Promoter_(genetics)

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Gene Promoter - an overview | ScienceDirect Topics

(2 days ago) A gene promoter is the genomic DNA sequence immediately upstream of the transcription start site. Generally, promoters are composed of a basal element where the general transcriptional machinery binds (e.g., RNA polymerase II and general TFs), and the proximal gene promoter that serves as a landing site for regulatory TFs. ...

https://www.sciencedirect.com/topics/medicine-and-dentistry/gene-promoter

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Promoter - Genome.gov

(2 days ago) A promoter is a sequence of DNA needed to turn a gene on or off. The process of transcription is initiated at the promoter. Usually found near the beginning of a gene, the promoter has a binding site for the enzyme used to make a messenger RNA (mRNA) molecule.

https://www.genome.gov/genetics-glossary/Promoter

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Gene Promoter - an overview | ScienceDirect Topics

(8 days ago) Gene Promoter. GPS carries out an exhaustive description of cis‐acting regulatory features, including the orientation, location, and number of binding sites for a regulatory protein, the presence of binding site submotifs, and the class and number of RNA polymerase sites (Fig. 3).

https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/gene-promoter

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What is a promoter and what does it do? | GMO Answers

(2 days ago) A promoter is the main regulatory portion of a gene. The simplest analogy is that a promoter is a “switch” that turns a gene “on” or “off.” It is the portion of the gene where cellular machinery binds before transcribing the DNA blueprint into a useful RNA.

https://gmoanswers.com/ask/what-promoter-and-what-does-it-do

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Promoter activity - Wikipedia

(16 days ago) Promoter activity is a term that encompasses several meanings around the process of gene expression from regulatory sequences —promoters and enhancers. Gene expression has been commonly characterized as a measure of how much, how fast, when and where this process happens. Promoters and enhancers are required for controlling where and when a specific gene is transcribed.

https://en.wikipedia.org/wiki/Promoter_activity

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Promoter region in Eukaryotes and Prokaryotes

(2 days ago) A promoter is a regulatory region of DNA located upstream (towards the 5' region) of of a gene, providing a control point for regulated gene transcription.. The promoter contains specific DNA sequences that are recognized by proteins known as transcription factors. These factors bind to the promoter sequences, recruiting RNA polymerase, the enzyme that synthesizes the RNA from the coding ...

http://www.scfbio-iitd.res.in/tutorial/promoter.html

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Find the location of a gene, and download the sequence for ...

(2 days ago) The promoter sequence that lies upstream, or 5', to the gene sequence is critical in regulating when and how the gene is turned on. To find the promoter region, use Map Viewer to locate the gene within a chromosomal context. Then increase the value of the coordinates that surround the gene to a larger sequence that includes the promoter.

https://www.ncbi.nlm.nih.gov/Class/MLACourse/Modules/Genomes/exercises/qa_mastery_per_map.html

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How can I find the promoter sequence of a gene on NCBI?

(7 days ago) Hi All, please could someone explain how exactly I get the promoter region of my gene from UCSC. I am a bit lost. Thanks. Cite. 2nd Feb, 2017. Ali Alavian-Ghavanini. University of Toronto.

https://www.researchgate.net/post/How_can_I_find_the_promoter_sequence_of_a_gene_on_NCBI

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Online Analysis Tools - Promoters

(1 days ago) Promoter and gene expression regulatory motifs search (Softberry, U.S.A.) - offers a variety of promoter-scanning programs CNNPromoter_e - Prediction of Eukaryotic Promoters by CNN models in genomic sequences. (Reference: Umarov RK, & Solovyev VV (2017) PLoS One. 12(2): e0171410

https://molbiol-tools.ca/Promoters.htm

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Promoters for Gene Expression | VectorBuilder

(2 days ago) Murine embryonic stem cell virus promoter including the enhancer and promoter region of PCMV virus and 5' untranslated region of dl-587rev retrovirus: Medium-strength promoter; drives gene expression in most murine or human ES cell lines and other mammalian cell lines. Proc Natl Acad Sci U S A. 87:9202(1990); Gene Ther. 1:136 (1994)

https://en.vectorbuilder.com/resources/vector-component/promoter.html

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Eukaryotic Gene Regulation | Boundless Biology

(2 days ago) Genes are organized to make the control of gene expression easier. The promoter region is immediately upstream of the coding sequence. This region can be short (only a few nucleotides in length) or quite long (hundreds of nucleotides long). The longer the promoter, the more available space for proteins to bind.

https://courses.lumenlearning.com/boundless-biology/chapter/eukaryotic-gene-regulation/

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Plasmids 101: The Promoter Region – Let's Go!

(3 days ago) Promoters are about 100 to 1000 base pairs long and found upstream of their target genes. The sequence of the promoter region controls the binding of the RNA polymerase and transcription factors, therefore promoters play a large role in determining where and when your gene of interest will be expressed.

https://blog.addgene.org/plasmids-101-the-promoter-region

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Promoter (genetics) - Simple English Wikipedia, the free ...

(10 days ago) In genetics, a promoter is a section of DNA which starts the transcription of a gene.. Promoters are near the genes they transcribe. They are on the same strand of DNA and are 'upstream'. Promoters can be about 100–1000 base pairs long.. Overview. For the transcription to take place, the enzyme that makes RNA, known as RNA polymerase, must attach to the DNA near a gene.

https://simple.wikipedia.org/wiki/Promoter_(genetics)

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Promoters - Addgene

(3 days ago) A promoter is a region of DNA where transcription of a gene is initiated. Promoters are a vital component of expression vectors because they control the binding of RNA polymerase to DNA. RNA polymerase transcribes DNA to mRNA which is ultimately translated into a functional protein.

https://www.addgene.org/mol-bio-reference/promoters/

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How to locate promoter sequence for a specific gene ...

(2 days ago) Here is the BRCA2 promoter sequence aligned to BRAC2 gene. In UCSC genome broswer, you can turn on CpG island feature, if there is CpG island in the promoter sequence, the sequence is highly likely a true promoter. In the above example (BRCA2), a CpG island is displayed in the proximal promoter. Beware some genes have alternative promoters.

https://signagen.com/blog/2015/10/14/how-to-locate-promoter-sequence-for-a-specific-gene/

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Promoter | genetics | Britannica

(3 days ago) In nucleic acid: Transcription …sequence on DNA called a promoter that signifies the start of the gene. The two strands of DNA become separated at this point, and RNA polymerase begins copying from a specific point on one strand of the DNA using a ribonucleoside 5′-triphosphate to begin the growing chain.

https://www.britannica.com/science/promoter-genetics

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Synpromics Synthetic Promoters for Gene Control | AskBio

(2 days ago) Promoters are sequences of DNA that sit beside each gene on the genome and whose function is to activate transcription, the initial process whereby a protein is synthesized from the gene template. Promoters regulate the activity of genes by controlling a gene’s ability to produce its own uniquely encoded protein.

https://www.askbio.com/gene-promoters/

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Management of Gene Promoter Mutations in Molecular ...

(7 days ago) The promoter of a gene. The promoter , a regulatory region of DNA located upstream of a gene, plays an important role in transcriptional regulation. The core promoter, a loosely defined region (approximately between nucleotides −40 and +50 from the transcriptional start site [TSS]), directs low-level transcription.

https://academic.oup.com/clinchem/article/55/4/698/5629367

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Gene promoter | definition of Gene promoter by Medical ...

(7 days ago) Srinivasan, "Alterations in gene promoter methylation and transcript expression induced by cisplatin in comparison to 5-azacytidine in HeLa and SiHa cervical cancer cell lines," Molecular and Cellular Biochemistry, vol.

https://medical-dictionary.thefreedictionary.com/Gene+promoter

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Promoter | Gene Design 1 - Gene Regions - passel

(10 days ago) The first region of a gene is the promoter.It acts as a 'genetic dimmer switch' in that it turns the gene on and off and specifies how many mRNA copies of the coding region to make. When more copies of mRNA are made, there are more mRNA strands available to be read by ribosomes during translation, and thus more protein can be produced. Two promoters currently used in transgenic crops are the ...

https://passel2.unl.edu/view/lesson/8bbd5bf3e412/3

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Difference Between Enhancer and Promoter | Compare the ...

(2 days ago) Key Difference – Enhancer vs Promoter Genes are the basic units of the heredity that consist of specific sequences of DNA. They contain information for the synthesis of functional proteins that are necessary for all the functions occurring in living organisms. The conversion of the information stored in the gene into a protein is known as gene expression, and it is a complex process.

https://www.differencebetween.com/difference-between-enhancer-and-vs-promoter/

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Cloning and functional analysis of the promoter of a ...

(11 months ago) Promoters are important DNA sequence signals in gene expression. Constitutive promoters can continuously drive transcription and expression of downstream genes, including exogenous genes. However, gene over expression may hinder the energy required for normal growth and the synthesis of RNA and proteins [1–3]. In contrast, inducible promoters ...

https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0211941

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Biology Ch 17 Flashcards | Quizlet

(29 days ago) A promoter is _____. (a) a protein that associates with bacterial RNA polymerase to help it bind to DNA (b) a sequence in RNA that promotes the release of RNA polymerase from DNA (c) a sequence in DNA that brings RNA polymerase near the site for transcription (d) one or more eukaryotic proteins that bind to DNA near the start of a gene

https://quizlet.com/95879504/biology-ch-17-flash-cards/

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11: Transcription: Promoters, terminators and mRNA ...

(5 days ago) C. Promoters and the Initiation of Transcription: General Properties. A promoter is the DNA sequence required for correct initiation of transcription; Phenotype of promoter mutants; a. cis‑acting: A cis-acting regulatory element functions as a segment of DNA to affect the expression of genes on the same chromosome that it is located on.

https://bio.libretexts.org/Bookshelves/Genetics/Book%3A_Working_with_Molecular_Genetics_(Hardison)/Unit_III%3A_The_Pathway_of_Gene_Expression/11%3A_Transcription%3A_Promoters_terminators_and_mRNA

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Promoter Sequence Search

(2 days ago) You want to predict the possible promoter region for your gene of interest? try to use some online tools like promoser etc. or if you want to have high confidence you can check for methylation marks in the region of interest. Usually for most of the genes the promoters lie with in 2kb (upstream) regions.

https://www.biostars.org/p/81774/

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Systematic Comparison of Constitutive Promoters and the ...

(8 days ago) Constitutive promoters are used routinely to drive ectopic gene expression. Here, we carried out a systematic comparison of eight commonly used constitutive promoters (SV40, CMV, UBC, EF1A, PGK and CAGG for mammalian systems, and COPIA and ACT5C for Drosophila systems). We also included in the comparison the TRE promoter, which can be activated by the rtTA transcriptional activator in a ...

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010611

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How to find the promoter region of a gene, given the ...

(6 days ago) If you are looking on-line tools for promoter prediction, I think that usually people take the region upstream their gene of interest and define an arbitrary length of the promoter (1000 bp to ...

https://www.researchgate.net/post/How-to-find-the-promoter-region-of-a-gene-given-the-genome-is-available

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Gene2Promoter: Retrieval and analysis of promoters

(4 days ago) Note: promoter sequences are always extracted in 5' → 3' direction. For a given list of input genes, Gene2Promoter provides the chromosomal location and a short description of the corresponding gene together with the promoters and alternative transcripts.

https://www.genomatix.de/online_help/help_eldorado/Gene2Promoter_Intro.html

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Promoters Used in Gene Regulation and its Types

(2 days ago) Regulation of gene expression at the promoter level is mainly controlled by the cis-acting elements localized upstream of the transcriptional start site Conserved eukaryotic promoter elements CAAT box: A consensus sequence close to -80 bp from the start point (+1). It plays an significant role in promoter efficiency, by increasing its strength.

https://www.biotecharticles.com/Biotech-Research-Article/Promoters-Used-in-Gene-Regulation-and-its-Types-3790.html

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Promoter-proximal pausing of RNA polymerase II: a nexus of ...

(29 days ago) Precise spatio-temporal control of gene activity is essential for organismal development, growth, and survival in a changing environment. Decisive steps in gene regulation involve the pausing of RNA polymerase II (Pol II) in early elongation, and the controlled release of paused polymerase into productive RNA synthesis.

https://pubmed.ncbi.nlm.nih.gov/31123063/

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Difference Between Eukaryotic and Prokaryotic Promoters ...

(3 days ago) The length of a promoter varies from 100 bp to 1000 bp. Promoters are different according to the type organism. Eukaryotic and prokaryotic promoters are different from each other. In prokaryotes, only three types of promoter sequences are found namely, -10 promoters, -35 promoter and upstream elements.

https://www.differencebetween.com/difference-between-eukaryotic-and-vs-prokaryotic-promoters/

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Promoter sequences | definition of promoter sequences by ...

(2 days ago) promoter sequences A length of DNA at the start of a gene to which molecules called transcription factors bind in order to control the activity of the gene either by blocking or increasing the production of messenger RNA.

https://medical-dictionary.thefreedictionary.com/promoter+sequences

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GAP Promoter Library for Fine-Tuning of Gene Expression in ...

(10 days ago) A library of engineered promoters of various strengths is a useful genetic tool that enables the fine-tuning and precise control of gene expression across a continuum of broad expression levels. The methylotrophic yeast Pichia pastoris is a well-established expression host with a large academic and industrial user base. To facilitate manipulation of gene expression spanning a wide dynamic ...

https://aem.asm.org/content/77/11/3600

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Local regulation of gene expression by lncRNA promoters ...

(2 days ago) For example, some gene promoters have been proposed to have dual functions as enhancers, and the process of transcription itself may contribute to gene regulation by recruiting activating factors or remodelling nucleosomes. Here we use genetic manipulation in mouse cell lines to dissect 12 genomic loci that produce lncRNAs and find that 5 of ...

https://pubmed.ncbi.nlm.nih.gov/27783602/

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gene | Definition, Structure, Expression, & Facts | Britannica

(3 days ago) Genes are made up of promoter regions and alternating regions of introns (noncoding sequences) and exons (coding sequences). The production of a functional protein involves the transcription of the gene from DNA into RNA, the removal of introns and splicing together of exons, the translation of the spliced RNA sequences into a chain of amino acids, and the posttranslational modification of the ...

https://www.britannica.com/science/gene

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Promoter (genetics) — Wikipedia Republished // WIKI 2

(5 months ago) As promoters are typically immediately adjacent to the gene in question, positions in the promoter are designated relative to the transcriptional start site, where transcription of DNA begins for a particular gene (i.e., positions upstream are negative numbers counting back from -1, for example -100 is a position 100 base pairs upstream).

https://wiki2.org/en/Promoter_(genetics)

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LSCF Bioinformatics - Sequence Analysis/Promoters

(2 days ago) Promoters in Groups of Genes. open in new window AlignACE - a program which finds sequence elements conserved in a set of DNA sequences from Church lab Download program open in new window Here; open in new window CREME - Cis-REgulatory Module Explorer 2.0; open in new window Gibbs motif sampler; open in new window MEME - The MEME/MAST System; open in new window MotifSampler - finds motifs in ...

https://bip.weizmann.ac.il/toolbox/seq_analysis/promoters.html

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11186 - Gene ResultRASSF1 Ras association domain family ...

(25 days ago) This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region.

https://www.ncbi.nlm.nih.gov/gene/11186

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MicroRNA-373 induces expression of genes with ...

(18 days ago) Recent studies have shown that microRNA (miRNA) regulates gene expression by repressing translation or directing sequence-specific degradation of complementary mRNA. Here, we report new evidence in which miRNA may also function to induce gene expression. By scanning gene promoters in silico for sequences complementary to known miRNAs, we identified a putative miR-373 target site in the ...

https://www.pnas.org/content/105/5/1608

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Gene promoter - definition of Gene promoter by The Free ...

(6 days ago) Define Gene promoter. Gene promoter synonyms, Gene promoter pronunciation, Gene promoter translation, English dictionary definition of Gene promoter. n. 1. One that promotes, especially an active supporter or advocate. 2. A financial and publicity organizer, as of a boxing match or an artistic...

https://www.thefreedictionary.com/Gene+promoter

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promoter region of gene - Biostar

(23 days ago) Thanks for the response. One more query, i have entered one gene to check the promoter sequence in UCSC genome browser, say for eg, EGFR and i got different promoter sequence for different transcript variant.

https://www.biostars.org/p/298528/

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Gene transcriptions/Boxes/TATAs - Wikiversity

(2 days ago) "The TATA box (also called Goldberg-Hogness box) is a DNA sequence (cis-regulatory element) found in the promoter region of genes in archaea and eukaryotes; approximately 24% of human genes contain a TATA box within the core promoter.

https://en.m.wikiversity.org/wiki/Gene_transcriptions/Boxes/TATAs

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Altmetric – Genomic Cloning and Promoter Analysis of ...

(7 hours ago) Using reporter gene transfection analysis, we found that a 2. 7-kb APEG-1 5'-flanking sequence directed a high level of promoter activity only in VSMC. Its activity was minimal in five other cell types. A repressor region located within an upstream 685-base pair sequence suppressed the activity of this 2.7-kb promoter.

https://www.altmetric.com/details/3510479

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Promoter - definition of promoter by The Free Dictionary

(5 days ago) Define promoter. promoter synonyms, promoter pronunciation, promoter translation, English dictionary definition of promoter. n. 1. One that promotes, especially an active supporter or advocate. ... (Genetics) genetics a sequence of nucleotides, associated with a structural gene, that must bind with messenger RNA polymerase before transcription ...

https://www.thefreedictionary.com/promoter

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Promoter | Definition of Promoter at Dictionary.com

(2 days ago) Promoter definition, a person or thing that promotes, furthers, or encourages. See more.

https://www.dictionary.com/browse/promoter

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Populus euphratica WRKY1 binds the promoter of H+-ATPase ...

(8 days ago) PeHA1-pro, the promoter of PeHA1, was cloned into the PMD18-T vector (Takara) and then transferred to a PBI121 vector. The promoter of PeHA1 was merged with the GUS gene and transformed into A. tumefaciens GV3101 (Shen et al., 2015a). PBI121-PeHA1-pro::GUS was finally transferred into WT tobacco using the leaf disc method (Shen et al., 2015a).

https://academic.oup.com/jxb/article/71/4/1527/5611324

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